Autor: Bálmis, Francisco Xavier (Javier.). Editorial: Paolo Giunchi, Ciudad: Roma Año: 1795. Encuadernación: Attractively bound in modern half leather. Páginas: viii + 154pp. Dimensiones: 13.5x20. Idioma: Italiano Ilustraciones: 2 folding copper plate engravings, one printed in green, the other in red (these plates are taken from the Spanish edition). Loosely inserted, three pages with notes in Latin in a contemporary hand. Uncut. Palau 22740. Wellcome online cat. EPB/B/12097. WorldCat records 7 copies in public libraries. Francisco Xavier (or Javier) de Balmis y Berenguer (Alicante, 1753 - Madrid, 1819) worked in hospìtals in Cuba and Mexico, where he studied the treatment with agave and begonia plants on venereal diseases. On his return to Spain, he became personal physician to Carlos IV, and persuaded the king to send an expedition to his American colonies to propogate the recently discovered vaccine for smallpox. He managed to persuade the reluctant vieroy of Mexico José de Iturrigaray to receive the treatment, and he and his team travelled throughout the American continents, from Texas to Chile to distribute the vaccine. After two years, in 1805, he travelled to the Philippines to further the work, spreading the vaccine as far as Macao and Cantón. This Real Expedición Filantrópica de la Vacun, or Expedición Balmis, hgas been the subjest of two novels (by US novelist Julia Álvarez and the Spanish writer Javier Moro) and a film for Spanish television.